Leukotrienes are non-cyclic monocarboxylic acids built from 20 carbon atoms; there are one or two oxygen substituents other than the three double bonds. They are also capable to induce inflammation but via a different pathway, but that inflammation is more severe compared to the PGE induced ones.
They are predominantly produced by cells of the immune system — macrophages, monocytes, neutrophils, and eosinophils. The cleavage (PLA2) is consistent with the