C1 units are essential for nucleotide synthesis, to keep enough in the human body we are following the transfer which starts from the folic acid.

Folic acid is a vitamin derivative that can be found in green salads for example. The proper level supports transmethylation by generating enough FH4 into the C1 cycle.

Figure 1. C1 transfer side

C1 transfer and its importance

  1. If you eat proper amount of green salad vitamin B9 gives you the folic acid.
  2. Folic acid is reduced by the Dihidrofolate-reductase (DHFR)

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