C1 units are essential for nucleotide synthesis, to keep enough in the human body we are following the transfer which starts from the folic acid.
Folic acid is a vitamin derivative that can be found in green salads for example. The proper level supports transmethylation by generating enough FH4 into the C1 cycle.
C1 transfer and its importance
- If you eat proper amount of green salad vitamin B9 gives you the folic acid.
- Folic acid is reduced by the Dihidrofolate-reductase (DHFR)