Questions
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- Define the term ‘anticipation’ in disease. Give two examples of diseases that express this phenomenon?
- Why are beta-thalassemia patients not discovered at birth?
- How is the Bombay blood group formed? What antigens are present in the serum of a person with this blood type?
- What other mutations apart from the LDL receptor mutation are responsible for Familial Hypercholesterolemia? How is this disease inherited?
- In Africa, about 97% of the population is Rh+. How many per cent of the population is a heterozygote?
- A heterozygous pea plant with round and yellow seed is crossed with a homozygous recessive pea plant with elongated and green seeds. Draw up the cross and state the phenotypic ratio of the F1 generation.
- A heterozygous pea plant with round and yellow seed is crossed with a homozygous recessive pea plant with elongated and green seeds. The F1 generation was crossed with each other; based on and the following ratios, what is the distance between the genes? Are the genes linked?
- Round and yellow: 415
- Round and green: 42
- Elongated and yellow: 50
- Elongated and green: 360
- In a population of 30000 people, 10000 of them have the O blood group. If 6000 of them are heterozygous for blood group A, calculate the allelic