Traditional therapies are those that help to influence and improve the diseased phenotype without directly acting on the gene or its expression.
- It is effective in about half of the people who take the treatment
There are six main traditional therapies:
- Activation of alternative metabolic pathways
- Blood transfusion
- Dietary Restriction
- Supplementing the missing molecule
- Protein Augmentation Therapy
- Enzyme Replacement Therapy
Activation of alternative metabolic pathways
- This is a therapy used to bypass certain metabolic pathways for alternative ones.
- It is usually used when the pathogenesis of the disease is due to the accumulation of a certain substance.
- For example, in Familial Hypercholesterolemia, the