Alzheimer's Disease
Alzheimer's disease is a multifactorial neurodegenerative disorder that is characterized by memory loss accompanied by confusion and difficulty in completing basic tasks.
- It has some forms that are early onset. They are monogenic and are inherited in an autosomal dominant pattern.
- It also has some sporadic forms that do not run in the family and arise as de novo mutations.
- It is caused by the deposition of amyloid proteins in the brain (amyloids are insoluble, fibrillary, misfolded proteins that are formed usually as a result of incomplete degradation or overproduction of a certain substance).
Huntington's Disease (HD)
Huntington's disease is a neurodegenerative disorder that is characterized by movement problems. One