Primary sclerosing cholangitis

Home » Pre-clinical » Pathology » Liver and gallbladder pathology » Primary sclerosing cholangitis

Autoimmune destruction and fibrosis of bile duct of all sizes, leading to dilation of preserved ducts

Seen as "beading" -- onion skin lesions
Common in ulcerative colitis
Associated with ANCA
Male predominance
Pancreatitis can appear due inflammation of common ducts

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