The structures of the CNS (brain and spinal cord) are covered by several layers of connective tissue; collectively, these connective tissue layers and the spaces between them are referred to as meninges.

Layers of the scalp, skull and brain -- Katie Ahlers -- CC BY-SA 4.0

The meninges show slight differences in the brain and spinal cord -- we will point them out at each stage.

Pia mater

The pia mater covers the brain and spinal cord.

  • Soft and delicate
  • Vascular

Pia mater is located right above the cerebral/cerebellar cortex, with a subpial space and a thin layer of glia limitans (see Neuroglial cells of the CNS lesson) separating them -- thus, pia mater does not come in direct contact with nerve bodies or fibers.

Pia mater contains collagen fibers (especially collagen

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