{"id":6828,"date":"2021-09-14T20:09:53","date_gmt":"2021-09-14T18:09:53","guid":{"rendered":"https:\/\/meddists.com\/learn\/pre-clinical\/pathology\/liver-pathology\/alpha-1-antitrypsin-deficiency\/"},"modified":"2021-09-14T20:10:34","modified_gmt":"2021-09-14T18:10:34","slug":"alpha-1-antitrypsin-deficiency","status":"publish","type":"page","link":"https:\/\/meddists.com\/learn\/pre-clinical\/pathology\/liver-and-gallbladder-pathology\/alpha-1-antitrypsin-deficiency\/","title":{"rendered":"Alpha-1-antitrypsin deficiency"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Misfolding of alpha1-antitrypsin (an inhibitor of elastase and proteinase-3) which is produced in the liver, leading to reduced plasma levels and accumulation within the liver:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Emphysema<\/li><li>Most clinically significant mutation is PiZ<\/li><\/ul>\n<div id=\"the_titles\" style=\"display:none;\"><\/div>","protected":false},"excerpt":{"rendered":"<p>Misfolding of alpha1-antitrypsin (an inhibitor of elastase and proteinase-3) which is produced in the liver, leading to reduced plasma levels and accumulation within the liver: Emphysema Most clinically significant mutation is PiZ<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":6822,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-6828","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Alpha-1-antitrypsin deficiency &#8211; 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