{"id":6807,"date":"2021-09-14T20:00:40","date_gmt":"2021-09-14T18:00:40","guid":{"rendered":"https:\/\/meddists.com\/learn\/pre-clinical\/pathology\/gastrointestinal-system\/infectious-enterocolitis\/"},"modified":"2021-09-14T20:05:10","modified_gmt":"2021-09-14T18:05:10","slug":"infectious-enterocolitis","status":"publish","type":"page","link":"https:\/\/meddists.com\/learn\/pre-clinical\/pathology\/gastrointestinal-system\/infectious-enterocolitis\/","title":{"rendered":"Infectious enterocolitis"},"content":{"rendered":"\n<ul class=\"wp-block-list\"><li>Routes of infection are usually fecal-oral<\/li><li>The gut is full of microbial flora<ul><li>Protects against colonization of pathogens<\/li><li>Breaks down indigestible food elements = symbiosis<\/li><li>Disruption of the natural microbial flora will lead to recurrent infections<\/li><\/ul><\/li><\/ul>\n\n\n<span class=\"block-heading\" id=\"header_1\">\n<h4 class=\"wp-block-heading\" class=\"wp-block-heading\" class=\"title_collection title1\">Pathogenic agents<\/h4>\n<\/span><span class=\"block-content\" id=\"contents_1\">\n\n\n<ul class=\"wp-block-list\"><li>Viruses<ul><li>Rotavirus<\/li><\/ul><\/li><li>Bacteria<ul><li>E. coli<\/li><li>Salmonella<\/li><li>Shigella<\/li><li>C. jejunum<\/li><\/ul><\/li><li>Parasites<\/li><\/ul>\n\n\n<\/span><span class=\"block-heading\" id=\"header_2\">\n<h4 class=\"wp-block-heading\" class=\"wp-block-heading\" class=\"title_collection title1\">Mechanisms in bacterial infections<\/h4>\n<\/span><span class=\"block-content\" id=\"contents_2\">\n\n\n<ul class=\"wp-block-list\"><li><strong>Ingestion of preformed toxins<\/strong><ul><li>S. aureus (enterotoxin)<\/li><\/ul><\/li><li><strong>Ingestion of toxin-producing bacteria<\/strong><ul><li>C. difficile<\/li><li>V. cholera<\/li><\/ul><\/li><li><strong>Ingestion of enteroinvasive bacteria<\/strong><ul><li>Shigella<\/li><li>Salmonella<\/li><\/ul><\/li><\/ul>\n\n\n<\/span><span class=\"block-heading\" id=\"header_3\">\n<h4 class=\"wp-block-heading\" class=\"wp-block-heading\" class=\"title_collection title1\">Morphology<\/h4>\n<\/span><span class=\"block-content\" id=\"contents_3\">\n\n\n<ul class=\"wp-block-list\"><li>Acute self-limited colitis will present with neutrophilic infiltration, cryptitis, and crypt abscesses<\/li><li>In V. cholera, the bacteria produce the <strong>cholera toxin<\/strong>, which causes ADP ribosylation and constant activation of a stimulatory G-protein, leading to chloride secretion and watery diarrhea<\/li><li>In C. difficile, the bacteria causes necrosis and fibrosis, leading to the formation of a pseudo-membrane<\/li><\/ul>\n<\/span><div id=\"the_titles\" style=\"display:none;\"><h4 class=\"wp-block-heading\" class=\"wp-block-heading\">Pathogenic agents<\/h4><h4 class=\"wp-block-heading\" class=\"wp-block-heading\">Mechanisms in bacterial infections<\/h4><h4 class=\"wp-block-heading\" class=\"wp-block-heading\">Morphology<\/h4><\/div>","protected":false},"excerpt":{"rendered":"<p>Routes of infection are usually fecal-oral The gut is full of microbial flora Protects against colonization of pathogens Breaks down indigestible food elements = symbiosis Disruption of the natural microbial flora will lead to recurrent infections Pathogenic agents Viruses Rotavirus Bacteria E. coli Salmonella Shigella C. jejunum Parasites Mechanisms in bacterial infections Ingestion of preformed [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":404,"menu_order":7,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-6807","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Infectious enterocolitis &#8211; 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