{"id":3050,"date":"2020-12-13T21:22:39","date_gmt":"2020-12-13T19:22:39","guid":{"rendered":"https:\/\/meddists.com\/learn\/pre-clinical\/histology\/neurohistology\/cerebellum\/cerebellum-introduction\/"},"modified":"2022-07-30T23:01:53","modified_gmt":"2022-07-30T21:01:53","slug":"cerebellum-introduction","status":"publish","type":"page","link":"https:\/\/meddists.com\/learn\/pre-clinical\/histology\/nervous-system\/cerebellum\/cerebellum-introduction\/","title":{"rendered":"Cerebellum &#8212; Introduction"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">In the cerebellum, much like the rest of the brain,&nbsp;the gray matter (cell bodies) is located outside while the white matter (nerve fibers) is on the inside. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">We can divide the cerebellum into two layers:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Gray matter<\/strong> &#8212; or <strong>cortex<\/strong><ul><li>Consisting of three distinct layers &#8212; Molecular, Purkinje, and granular layers<\/li><li>Some authors refer to the Purkinje layer as part of the molecular layer<\/li><\/ul><\/li><li><strong>White matter<\/strong>\u00a0&#8212; or <strong>medulla\u00a0<\/strong>(and sometimes &#8220;lamina alba&#8221;) &#8212; Nerve fibers<\/li><\/ul>\n\n\n\n<p class=\"wp-block-paragraph\"><em>Do not forget that the cerebellum is covered by the <strong>meninges<\/strong>.<\/em><\/p>\n\n\n<span class=\"block-heading\" id=\"header_1\">\n<h3 class=\"wp-block-heading\" class=\"wp-block-heading\" class=\"title_collection title1\">Cerebellar cell population<\/h3>\n<\/span><span class=\"block-content\" id=\"contents_1\">\n\n\n<p class=\"wp-block-paragraph\">Within the cortex of the cerebellum, just as with the cerebrum, we can find several types of neuron cells.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>They have excitatory\/inhibitory functions (discussed in the next article)<\/li><li>In standard H&amp;E slides, only Purkinje cells are clearly distinguishable<\/li><\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Apart from neurons, the cerebellum is packed full with&nbsp;neuroglial cells &#8212; these are the same neuroglial cells of the CNS we&#8217;ve covered before, with additional types that can be identified in sections of the cerebellum, such as the Bergmann glial cells.<\/p>\n\n\n<\/span><span class=\"block-heading\" id=\"header_2\">\n<h4 class=\"wp-block-heading\" class=\"wp-block-heading\" class=\"title_collection title2\">Bergmann glial cells<\/h4>\n<\/span><span class=\"block-content\" id=\"contents_2\">\n\n\n<ul class=\"wp-block-list\"><li>Also known as radial epithelial cells<\/li><li>During the development of the cerebellum, they assist the migration of Purkinje and Granular cells<\/li><li>Function similarly to astrocytes<\/li><li>Respond to CNS damage (<strong>gliosis<\/strong> &#8212; formation of glial scar in sites of injury or stroke)<\/li><\/ul>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter\"><a href=\"http:\/\/meddists.com\/wp-content\/uploads\/2019\/01\/Screenshot_23.png\" target=\"_blank\" title=\"Cerebellum -- Introduction\"><img decoding=\"async\" src=\"http:\/\/meddists.com\/wp-content\/uploads\/2019\/01\/Screenshot_23-600x571.png\" alt=\"\" class=\"wp-image-8725\"\/><\/a><figcaption><strong>Bergmann cell processes<\/strong><\/figcaption><\/figure>\n<\/div><\/span><div id=\"the_titles\" style=\"display:none;\"><h3 class=\"wp-block-heading\" class=\"wp-block-heading\">Cerebellar cell population<\/h3><h4 class=\"wp-block-heading\" class=\"wp-block-heading\">Bergmann glial cells<\/h4><\/div>","protected":false},"excerpt":{"rendered":"<p>In the cerebellum, much like the rest of the brain,&nbsp;the gray matter (cell bodies) is located outside while the white matter (nerve fibers) is on the inside. We can divide the cerebellum into two layers: Gray matter &#8212; or cortex Consisting of three distinct layers &#8212; Molecular, Purkinje, and granular layers Some authors refer to [&hellip;]<\/p>\n","protected":false},"author":23,"featured_media":0,"parent":3030,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-3050","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.8 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Cerebellum -- Introduction &#8211; Meddists<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/meddists.com\/learn\/pre-clinical\/histology\/nervous-system\/cerebellum\/cerebellum-introduction\/\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/meddists.com\\\/learn\\\/pre-clinical\\\/histology\\\/nervous-system\\\/cerebellum\\\/cerebellum-introduction\\\/\",\"url\":\"https:\\\/\\\/meddists.com\\\/learn\\\/pre-clinical\\\/histology\\\/nervous-system\\\/cerebellum\\\/cerebellum-introduction\\\/\",\"name\":\"Cerebellum -- Introduction &#8211; 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