{"id":2341,"date":"2020-09-21T12:18:24","date_gmt":"2020-09-21T10:18:24","guid":{"rendered":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/sports-biochemistry\/interaction-between-exercised-induced-master-regulators-ampk-sirt1-pgc1%ce%b1\/"},"modified":"2020-09-21T12:52:50","modified_gmt":"2020-09-21T10:52:50","slug":"interaction-between-exercised-induced-master-regulators-ampk-sirt1-pgc1%ce%b1","status":"publish","type":"page","link":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-tissues\/sports-biochemistry\/interaction-between-exercised-induced-master-regulators-ampk-sirt1-pgc1%ce%b1\/","title":{"rendered":"Interaction between exercised induced Master Regulators: AMPK, SIRT1, PGC1\u03b1"},"content":{"rendered":"<span class=\"block-heading\" id=\"header_1\">\n<h4 class=\"wp-block-heading\" class=\"wp-block-heading\" class=\"title_collection title1\">Interaction between exercise-induced Master Regulators<\/h4>\n<\/span><span class=\"block-content\" id=\"contents_1\">\n\n\n<ol class=\"wp-block-list\"><li>AMPK (cooperating with SIRT1 activates PGC-1\u03b1)<\/li><li>SIRT1 (cooperating with AMPK activates PGC-1\u03b1)<\/li><li>PGC1\u03b1 (increase the rate of transcription its own gene and activates the mitochondrial biogenesis)<\/li><\/ol>\n\n\n<\/span><span class=\"block-heading\" id=\"header_2\">\n<h4 class=\"wp-block-heading\" class=\"wp-block-heading\" class=\"title_collection title1\">The gene expression of skeletal muscle is regulated by exercise<\/h4>\n<\/span><span class=\"block-content\" id=\"contents_2\">\n\n\n<ol class=\"wp-block-list\"><li>PGC1\u03b1 (increase the rate of transcription of its own gene and activates the mitochondrial biogenesis, activates PPAR\u03b4).<\/li><li>PPAR\u03b4 is a transcriptional regulator of gene expression in skeletal muscle<ol><li>Regulatory activity is modified by exercise.<\/li><li>Interaction between AMPK and PPAR\u03b4 contributes to the reprogramming of the skeletal muscle transcriptome.<\/li><li>Chronic inflammation is prevented by regular exercise, inducing elevated level a PGC1\u03b1.<\/li><\/ol><\/li><\/ol>\n<\/span><div id=\"the_titles\" style=\"display:none;\"><h4 class=\"wp-block-heading\" class=\"wp-block-heading\">Interaction between exercise-induced Master Regulators<\/h4><h4 class=\"wp-block-heading\" class=\"wp-block-heading\">The gene expression of skeletal muscle is regulated by exercise<\/h4><\/div>","protected":false},"excerpt":{"rendered":"<p>Interaction between exercise-induced Master Regulators AMPK (cooperating with SIRT1 activates PGC-1\u03b1) SIRT1 (cooperating with AMPK activates PGC-1\u03b1) PGC1\u03b1 (increase the rate of transcription its own gene and activates the mitochondrial biogenesis) The gene expression of skeletal muscle is regulated by exercise PGC1\u03b1 (increase the rate of transcription of its own gene and activates the mitochondrial [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":278,"menu_order":8,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-2341","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Interaction between exercised induced Master Regulators: AMPK, SIRT1, PGC1\u03b1 &#8211; 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