{"id":1839,"date":"2020-08-18T13:26:45","date_gmt":"2020-08-18T13:26:45","guid":{"rendered":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/lipid-metabolism\/roles-of-fatty-acids\/"},"modified":"2021-10-26T17:02:51","modified_gmt":"2021-10-26T15:02:51","slug":"roles-of-fatty-acids","status":"publish","type":"page","link":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/lipid-metabolism\/roles-of-fatty-acids\/","title":{"rendered":"Roles of Fatty Acids"},"content":{"rendered":"\n

Fatty acids are essential for the proper cell signalling, blood coagulation, inflammation and basic homeostasis of the cells <\/div><\/p>\n\n\n\n

The role of the saturated fatty acids<\/h2>\n<\/span>\n\n\n
  1. Formation of triacylglycerol molecules (TAGs) for the storage of the excess amount of energy in adipose tissue<\/li>
  2. They are involved in the biochemistry of cholesterol metabolism (VLDL\/LDL).<\/li><\/ol>\n\n\n<\/span>\n

    Palmitate C16<\/sub> (Palmitic acid)<\/h2>\n<\/span>\n\n\n

    Every fatty acid synthesis begins with palmitate<\/strong>, after which it is needed, elongated by different processes generating longer and different fatty acids.<\/p>\n\n\n\n

    Palmitate is considered the most abundant saturated fatty acid in animals and plants<\/em><\/p>\n\n\n<\/span>\n

    The role of the unsaturated fatty acids<\/h2>\n<\/span>\n\n\n

    Unsaturated fatty acids are involved in different processes, of which the most important one is the production of the prostaglandin (PGE) molecules during inflammation.<\/p>\n\n\n\n

    Unsaturated fatty acids are said to \u201cboost the brain\u201d because they make up the myelin sheath, covering axons, and leading to faster and better nerve conduction.<\/em> That is the reason why people are saying before the exam to take some fish oil capsules… however, the truth is that is not going to be absorbed by your body, you need to eat real fish to get the proper amount (sorry guys, but yeah most of these tablets are waste of money).<\/em><\/p>\n\n\n<\/span>\n

    Arachidonic acid C20<\/sub><\/h2>\n<\/span>\n\n\n
    \"\"<\/a>
    Figure 1. Arachidonic acid\/PLA2<\/sub> pathway<\/strong><\/figcaption><\/figure><\/div>\n\n\n\n

    Arachidonic acid<\/strong> is an unsaturated fatty acid taking place in the structure of the cellular membrane as a phospholipid<\/strong> component, which could be cleaved out from it, upon activation of the PLA2<\/sub><\/strong> enzyme.<\/p>\n\n\n\n

    After being cleaved by the PLA2<\/sub>\u00a0enzyme the arachidonic acid divide into two pathways with the help of Cyclooxygenase (COX)<\/strong> or lipoxygenase<\/strong> enzymes. <\/p>\n\n\n<\/span>\n

    References<\/h2>\n<\/span>\n\n\n

    Snider MDS. Devlin\u2019s Textbook of Biochemistry with Clinical Correlations<\/strong>, the 8th Edition. John Wiley & Sons, Incorporated, 2020; 2019.<\/span> <\/p>\n<\/span>

    The role of the saturated fatty acids<\/h2>

    Palmitate C16<\/sub> (Palmitic acid)<\/h2>

    The role of the unsaturated fatty acids<\/h2>

    Arachidonic acid C20<\/sub><\/h2>

    References<\/h2><\/div>","protected":false},"excerpt":{"rendered":"

    The role of the saturated fatty acids Formation of triacylglycerol molecules (TAGs) for the storage of the excess amount of energy in adipose tissue They are involved in the biochemistry of cholesterol metabolism (VLDL\/LDL). Palmitate C16 (Palmitic acid) Every fatty acid synthesis begins with palmitate, after which it is needed, elongated by different processes generating […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1712,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1839","page","type-page","status-publish","hentry"],"yoast_head":"\nRoles of Fatty Acids – Meddists<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/lipid-metabolism\/roles-of-fatty-acids\/\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" 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