{"id":1731,"date":"2020-08-14T17:32:47","date_gmt":"2020-08-14T17:32:47","guid":{"rendered":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/carbohydrate-metabolism\/glycogen-degradation\/"},"modified":"2021-10-13T14:41:30","modified_gmt":"2021-10-13T12:41:30","slug":"glycogen-degradation","status":"publish","type":"page","link":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/carbohydrate-metabolism\/glycogen-degradation\/","title":{"rendered":"Glycogen degradation – Glycogenolysis"},"content":{"rendered":"\n

The degradation of the glycogen means that the glucose line is going to be utilised, glucose by glucose with the help of the glycogen phosphorylase enzyme <\/div><\/p>\n\n\n\n

Description<\/h2>\n<\/span>\n\n\n

The process of glycogen degradation is known as\u00a0glycogenolysis<\/strong>.\u00a0Glycogenolysis occurs in the liver and muscles and is triggered by hormonal signalling by hunger or stress.<\/p>\n\n\n<\/span>\n

Steps of the degradation<\/h2>\n<\/span>\n\n\n
  1. Glycogen phosphorylase<\/strong>\u00a0activated by insuline or glucagon and phosphorylates one glucose from the chain, glucose-1-P is generated<\/li>
  2. Repeating the previous step until it reaches the last glucose in the line<\/li>
  3. DEBRANCHING ENZYME \u0391-1,4-TRANSGLYCOSYLASE<\/strong>\u00a0is going to remove the branching point<\/li>
  4. DEBRANCHING ENZYME \u0391-1,6-GLUCOSIDASE<\/strong> will generate a single line without branches<\/li>
  5. Free glucose will be metabolized in different tissues, or even within the muscle depending on the current need of the body<\/li><\/ol>\n\n\n\n
    \"\"<\/a>
    Figure 1. Glycogenolysis<\/strong><\/figcaption><\/figure><\/div>\n\n\n<\/span>\n

    References<\/h2>\n<\/span>\n\n\n

    Snider MDS. Devlin\u2019s Textbook of Biochemistry with Clinical Correlations<\/strong>, the 8th Edition. John Wiley & Sons, Incorporated, 2020; 2019.<\/span> <\/p>\n<\/span>

    Description<\/h2>

    Steps of the degradation<\/h2>

    References<\/h2><\/div>","protected":false},"excerpt":{"rendered":"

    Description The process of glycogen degradation is known as\u00a0glycogenolysis.\u00a0Glycogenolysis occurs in the liver and muscles and is triggered by hormonal signalling by hunger or stress. Steps of the degradation Glycogen phosphorylase\u00a0activated by insuline or glucagon and phosphorylates one glucose from the chain, glucose-1-P is generated Repeating the previous step until it reaches the last glucose […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1711,"menu_order":16,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1731","page","type-page","status-publish","hentry"],"yoast_head":"\nGlycogen degradation - Glycogenolysis – Meddists<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/carbohydrate-metabolism\/glycogen-degradation\/\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/meddists.com\\\/learn\\\/pre-clinical\\\/biochemistry\\\/biochemistry-of-the-metabolism\\\/carbohydrate-metabolism\\\/glycogen-degradation\\\/\",\"url\":\"https:\\\/\\\/meddists.com\\\/learn\\\/pre-clinical\\\/biochemistry\\\/biochemistry-of-the-metabolism\\\/carbohydrate-metabolism\\\/glycogen-degradation\\\/\",\"name\":\"Glycogen degradation - 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