{"id":1730,"date":"2020-08-14T17:32:47","date_gmt":"2020-08-14T17:32:47","guid":{"rendered":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/carbohydrate-metabolism\/glycogen-synthesis\/"},"modified":"2021-10-13T14:21:00","modified_gmt":"2021-10-13T12:21:00","slug":"glycogen-synthesis","status":"publish","type":"page","link":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/carbohydrate-metabolism\/glycogen-synthesis\/","title":{"rendered":"Glycogen synthesis – Glycogenesis"},"content":{"rendered":"\n

Glycogen is the stored form of glucose in the muscle and liver tissues. It is a complex molecule with hundreds of glucose units inside <\/div><\/p>\n\n\n\n

Glycogen \u2014 Description<\/h2>\n<\/span>\n\n\n

Glycogen is one of the ways our body stores excess amounts of glucose. The glycogen molecule is composed of hundreds of single activated glucose molecules, specific to the muscle and liver tissues (Figure 1<\/strong>).<\/p>\n\n\n<\/span>\n

Synthesis of glycogen<\/h2>\n<\/span>\n\n\n

The glycogenesis stems from the glycolytic pathway and occurs within muscle and liver tissues initiated from glucose-6-P<\/strong>. <\/p>\n\n\n\n

Glucose 6-P<\/strong> changes into glucose-1-P<\/strong> via phosphoglucomutase.<\/p>\n\n\n\n

\"\"<\/a>
Figure 2. Glycogen synthesis<\/strong><\/figcaption><\/figure><\/div>\n\n\n\n

UDP<\/strong> will be added to the glucose-1-P, resulting in the \u201cactivated glucose<\/strong>\u201c.
<\/p>\n\n\n\n

Glycogenin <\/strong>(primer protein) is taking the activated glucose while the UDP released from it
<\/p>\n\n\n\n

Another round comes and the chain of activated glucose increases.<\/p>\n\n\n\n

After the length of the first line reaches the maximum branching is going to happen (BRANCHING ENZYME<\/strong>)
<\/p>\n\n\n<\/span>\n

References<\/h2>\n<\/span>\n\n\n

Snider MDS. Devlin\u2019s Textbook of Biochemistry with Clinical Correlations<\/strong>, the 8th Edition. John Wiley & Sons, Incorporated, 2020; 2019.<\/span> <\/p>\n<\/span>

Glycogen \u2014 Description<\/h2>

Synthesis of glycogen<\/h2>

References<\/h2><\/div>","protected":false},"excerpt":{"rendered":"

Glycogen \u2014 Description Glycogen is one of the ways our body stores excess amounts of glucose. The glycogen molecule is composed of hundreds of single activated glucose molecules, specific to the muscle and liver tissues (Figure 1). Synthesis of glycogen The glycogenesis stems from the glycolytic pathway and occurs within muscle and liver tissues initiated from glucose-6-P. 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