{"id":1727,"date":"2020-08-14T17:32:44","date_gmt":"2020-08-14T17:32:44","guid":{"rendered":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/carbohydrate-metabolism\/the-cory-cycle\/"},"modified":"2021-10-04T22:50:13","modified_gmt":"2021-10-04T20:50:13","slug":"the-cory-cycle","status":"publish","type":"page","link":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/carbohydrate-metabolism\/the-cory-cycle\/","title":{"rendered":"The Cory-cycle"},"content":{"rendered":"\n

The Cory cycle is a pathway in which:<\/p>\n\n\n\n
  1. lactate produced by anaerobic glycolysis (less amount of oxygen) in muscles <\/li>
  2. lactate is transported to the liver and converted to glucose<\/li>
  3. glucose returns to the muscles and metabolized back to lactate<\/div><\/li><\/ol>\n\n\n\n

    Gluconeogenesis – Cory-cycle<\/h2>\n<\/span>\n\n\n
    \"\"<\/a>
    Figure 1.  Lactate production and lactate shuttle<\/strong><\/figcaption><\/figure><\/div>\n\n\n\n

    Gluconeogenesis works with lactate, which is the end product of anaerobic glycolysis.<\/p>\n\n\n\n

    Most lactate is produced in red blood cells and active muscles (relative hypoxia); after which, the lactate circulates into the liver and turns back into glucose \u2014 this is the Cory-cycle \u2014 a part of the gluconeogenesis (Figure 1<\/strong>). The Cory-cycle is the metabolization of lactate in different tissue as it has been produced.<\/p>\n\n\n\n

    If the muscle produces lactate with the blood, it is going towards to liver, and in the liver, gluconeogenesis proceeds from lactate via\u00a0pyruvate<\/strong>\u00a0and gluconeogenesis generating glucose back.<\/p>\n\n\n\n

    This glucose is used for the production of ATP with the TCA cycle, which process is similar to the Lactate cycle from the previous topic (Figure 2<\/strong>).<\/p>\n\n\n\n

    \"\"<\/a>
    Figure 2.  Cory-cycle<\/strong><\/figcaption><\/figure><\/div>\n\n\n<\/span>\n

    References <\/h2>\n<\/span>\n\n\n

    Snider MDS. Devlin\u2019s Textbook of Biochemistry with Clinical Correlations<\/strong>, the 8th Edition. John Wiley & Sons, Incorporated, 2020; 2019.<\/span> <\/p>\n<\/span>

    Gluconeogenesis – Cory-cycle<\/h2>

    References <\/h2><\/div>","protected":false},"excerpt":{"rendered":"

    Gluconeogenesis – Cory-cycle Gluconeogenesis works with lactate, which is the end product of anaerobic glycolysis. Most lactate is produced in red blood cells and active muscles (relative hypoxia); after which, the lactate circulates into the liver and turns back into glucose \u2014 this is the Cory-cycle \u2014 a part of the gluconeogenesis (Figure 1). The […]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1711,"menu_order":12,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-1727","page","type-page","status-publish","hentry"],"yoast_head":"\nThe Cory-cycle – Meddists<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/carbohydrate-metabolism\/the-cory-cycle\/\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/meddists.com\\\/learn\\\/pre-clinical\\\/biochemistry\\\/biochemistry-of-the-metabolism\\\/carbohydrate-metabolism\\\/the-cory-cycle\\\/\",\"url\":\"https:\\\/\\\/meddists.com\\\/learn\\\/pre-clinical\\\/biochemistry\\\/biochemistry-of-the-metabolism\\\/carbohydrate-metabolism\\\/the-cory-cycle\\\/\",\"name\":\"The Cory-cycle – Meddists\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/meddists.com\\\/learn\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/meddists.com\\\/learn\\\/pre-clinical\\\/biochemistry\\\/biochemistry-of-the-metabolism\\\/carbohydrate-metabolism\\\/the-cory-cycle\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/meddists.com\\\/learn\\\/pre-clinical\\\/biochemistry\\\/biochemistry-of-the-metabolism\\\/carbohydrate-metabolism\\\/the-cory-cycle\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/meddists.com\\\/learn\\\/wp-content\\\/uploads\\\/2021\\\/10\\\/Cory-cycle-1024x638.png\",\"datePublished\":\"2020-08-14T17:32:44+00:00\",\"dateModified\":\"2021-10-04T20:50:13+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/meddists.com\\\/learn\\\/pre-clinical\\\/biochemistry\\\/biochemistry-of-the-metabolism\\\/carbohydrate-metabolism\\\/the-cory-cycle\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/meddists.com\\\/learn\\\/pre-clinical\\\/biochemistry\\\/biochemistry-of-the-metabolism\\\/carbohydrate-metabolism\\\/the-cory-cycle\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\\\/\\\/meddists.com\\\/learn\\\/pre-clinical\\\/biochemistry\\\/biochemistry-of-the-metabolism\\\/carbohydrate-metabolism\\\/the-cory-cycle\\\/#primaryimage\",\"url\":\"https:\\\/\\\/meddists.com\\\/learn\\\/wp-content\\\/uploads\\\/2021\\\/10\\\/Cory-cycle.png\",\"contentUrl\":\"https:\\\/\\\/meddists.com\\\/learn\\\/wp-content\\\/uploads\\\/2021\\\/10\\\/Cory-cycle.png\",\"width\":1600,\"height\":997},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/meddists.com\\\/learn\\\/pre-clinical\\\/biochemistry\\\/biochemistry-of-the-metabolism\\\/carbohydrate-metabolism\\\/the-cory-cycle\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"http:\\\/\\\/meddists.com\\\/learn\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Pre-clinical\",\"item\":\"https:\\\/\\\/meddists.com\\\/learn\\\/pre-clinical\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Biochemistry\",\"item\":\"https:\\\/\\\/meddists.com\\\/learn\\\/pre-clinical\\\/biochemistry\\\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"Biochemistry of the metabolism\",\"item\":\"https:\\\/\\\/meddists.com\\\/learn\\\/pre-clinical\\\/biochemistry\\\/biochemistry-of-the-metabolism\\\/\"},{\"@type\":\"ListItem\",\"position\":5,\"name\":\"Carbohydrate metabolism\",\"item\":\"https:\\\/\\\/meddists.com\\\/learn\\\/pre-clinical\\\/biochemistry\\\/biochemistry-of-the-metabolism\\\/carbohydrate-metabolism\\\/\"},{\"@type\":\"ListItem\",\"position\":6,\"name\":\"The Cory-cycle\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/meddists.com\\\/learn\\\/#website\",\"url\":\"https:\\\/\\\/meddists.com\\\/learn\\\/\",\"name\":\"Meddists\",\"description\":\"Let's Get Studying\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/meddists.com\\\/learn\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"The Cory-cycle – Meddists","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/carbohydrate-metabolism\/the-cory-cycle\/","twitter_misc":{"Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/carbohydrate-metabolism\/the-cory-cycle\/","url":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/carbohydrate-metabolism\/the-cory-cycle\/","name":"The Cory-cycle – Meddists","isPartOf":{"@id":"https:\/\/meddists.com\/learn\/#website"},"primaryImageOfPage":{"@id":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/carbohydrate-metabolism\/the-cory-cycle\/#primaryimage"},"image":{"@id":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/carbohydrate-metabolism\/the-cory-cycle\/#primaryimage"},"thumbnailUrl":"https:\/\/meddists.com\/learn\/wp-content\/uploads\/2021\/10\/Cory-cycle-1024x638.png","datePublished":"2020-08-14T17:32:44+00:00","dateModified":"2021-10-04T20:50:13+00:00","breadcrumb":{"@id":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/carbohydrate-metabolism\/the-cory-cycle\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/carbohydrate-metabolism\/the-cory-cycle\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/carbohydrate-metabolism\/the-cory-cycle\/#primaryimage","url":"https:\/\/meddists.com\/learn\/wp-content\/uploads\/2021\/10\/Cory-cycle.png","contentUrl":"https:\/\/meddists.com\/learn\/wp-content\/uploads\/2021\/10\/Cory-cycle.png","width":1600,"height":997},{"@type":"BreadcrumbList","@id":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/carbohydrate-metabolism\/the-cory-cycle\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"http:\/\/meddists.com\/learn\/"},{"@type":"ListItem","position":2,"name":"Pre-clinical","item":"https:\/\/meddists.com\/learn\/pre-clinical\/"},{"@type":"ListItem","position":3,"name":"Biochemistry","item":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/"},{"@type":"ListItem","position":4,"name":"Biochemistry of the metabolism","item":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/"},{"@type":"ListItem","position":5,"name":"Carbohydrate metabolism","item":"https:\/\/meddists.com\/learn\/pre-clinical\/biochemistry\/biochemistry-of-the-metabolism\/carbohydrate-metabolism\/"},{"@type":"ListItem","position":6,"name":"The Cory-cycle"}]},{"@type":"WebSite","@id":"https:\/\/meddists.com\/learn\/#website","url":"https:\/\/meddists.com\/learn\/","name":"Meddists","description":"Let's Get Studying","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/meddists.com\/learn\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/meddists.com\/learn\/wp-json\/wp\/v2\/pages\/1727","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/meddists.com\/learn\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/meddists.com\/learn\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/meddists.com\/learn\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/meddists.com\/learn\/wp-json\/wp\/v2\/comments?post=1727"}],"version-history":[{"count":9,"href":"https:\/\/meddists.com\/learn\/wp-json\/wp\/v2\/pages\/1727\/revisions"}],"predecessor-version":[{"id":7595,"href":"https:\/\/meddists.com\/learn\/wp-json\/wp\/v2\/pages\/1727\/revisions\/7595"}],"up":[{"embeddable":true,"href":"https:\/\/meddists.com\/learn\/wp-json\/wp\/v2\/pages\/1711"}],"wp:attachment":[{"href":"https:\/\/meddists.com\/learn\/wp-json\/wp\/v2\/media?parent=1727"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}