Lipid metabolism disorders, classification, complications

Introduction

Lipid metabolism disorders are characterized by an increased serum concentration of lipoproteins and/or lipids (dyslipidemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia).

• Dyslipidemia is a disturbance in the balance of the serum lipids (elevated VLDL and LDL, and decreased HDL)
• Generally, VLDL and LDL contribute to the development of atherosclerosis, while HDL is considered protective against it.
• Lipid metabolism disorders can be primary or secondary.
  • Primary lipid metabolism disorders are congenital.
  • Secondary lipid metabolism disorders result from obesity, diabetes, liver and billiary disorders, hypothyroidism, renal disease, and certain drugs (ethanol, thiazides, glucocorticoids).
• Presents with systemic atherosclerosis (CAD, peripheral arterial disease, renal

Introduction

Primary lipid metabolism disorders

Classification

Examples

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