Introduction

Lipid-lowering treatment is important in controlling and preventing atherosclerosis.

  • Hyper- and dyslipidemias can be inherited or acquired.
  • Reduced LDL and triglyceride levels are associated with a reduced risk of atherosclerosis and cardiovascular disease.
  • Lipid-lowering treatment involves:
    • Lifestyle modifications
    • Treatment of secondary causes for the hyper- and dyslipidemias (DM, hypothyroidism)
    • Lipid-lowering drugs

Lifestyle modifications

  • Weight loss
  • Dietary changes
  • Exercise

Lipid-lowering drugs

  • Statins
  • Ezetimibe
  • Anti-PCSK9 monoclonal antibodies

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