Sjögren’s syndrome: symptoms, diagnosis, treatment

Sjögren’s syndrome is a chronic autoimmune disease characterized by the destruction of the salivary and lacrimal glands.

• Presents with dry eyes (xeropthalmia) and dry mouth (xerostomia).
• Lymphocytes (mostly T-helper cells) infiltrate salivary and lacrimal glandular tissues and destroy it (type IV hypersensitivity).
• Increased risk for NHL, which is the most common cause of death.

Forms

Clinical presentation

Diagnosis

Treatment

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