Idiopathic inflammatory myopathies (IIM) are a collective name for a heterogeneous group of disorders, characterized by inflammatory changes in the muscles and other tissues.
Classification
IIM can be classified into 4 groups:
- Dermatomyositis (DM)
- Overlap myositis (OM)
- Inclusion body myositis (IBM)
- Necrotizing autoimmune myopathy (NAM)
Some authors refer to polymyositis (PM) as a member of IIM, while others describe it as a CTD-associated myositis.
Clinical presentation
- All of the IIMs except for IBM present with proximal muscle weakness with elevated CK levels.
- IBM presents